Products
Nanoparticles
NanoVex Biotechnologies designs, develops and produces two main types of nanomaterials: nanovesicles and metallic nanoparticles
Neuroscience
FIVEphoton Biochemicals
FIVEphoton Biochemicals, a domestic and international supplier, provides high quality, reliable and validated research kits and reagents to scientists in life science corporations and academic laboratories to excel in their experimentation.
FD NeuroTechnologies, Inc.
FD NeuroTechnologies, Inc. is a unique biotechnology company dedicated to the morphological studies of the central nervous system. Established in 1996, their products and services have been utilized internationally. They are highly regarded experts in the fields of neurohistology, neurohistopathology, and immunohistochemistry, with hundreds of citations in peer-review journals. Their most widely cited staining kits include FD Rapid GolgiStain Kit, FD MultiStain Kit, FD NeuroApop Kit, and FD NeuroSilver Kit II.
Flow Cytometry
pluriMate
pluriMate is a new PBMC isolation aid for perfect blood overlay every time. pluriMate dramatically assists the researcher in obtaining quick, consistent results.
pluriMate® was developed for optimal separation of leukocytes and peripheral blood mononuclear cells (PBMC) from whole blood and bone marrow. The key feature of pluriMate® is the porous sponge incorporated at the bottom of the centrifuge tube. This barrier consists of high-grade polyurethane. It prevents you from time-consuming and laborious overlaying of the sample material. Anticoagulated blood or bone marrow can simply be poured directly from the blood sampling tube into the pluriMate® tube. The porous barrier prevents mixture of the sample material with the separation medium. During centrifugation, leucocytes, lymphocytes and PBMCs are separated from unwanted erythrocytes and granulocytes, depending on the density gradient used (Leuko Spin, Lympho Spin, PLT Spin etc.) on the basis of their density and enriched in an interphase above the separation medium. When separation is complete, the barrier prevents recontamination of the enriched cell fraction during harvest. Regardless of whether large or small sample volumes are to be processed.
Proteomics & Crosslinkers
Biotech Support Group
Biomarker discovery for personalized heath care monitoring in the future.
Biotech Support Group creates new methods and applications to drive better data quality and efficient workflows for all proteomic and biomarker analyses.
ProteoChem
ProteoChem manufactures analytical standards for NMR and mass spectrometry, protein crosslinkers, and novel proteomics reagents for protein detection and protein modification used in mass spectrometry, drug development, diagnostics, and protein biology.
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Biobank Sample Storage Systems
SAFE® “Store Aliquot Samples For Ever”.
Samplosophy® storage tubes are designed for long term careful storage of biological materials, including human and animal biospecimens, cell cultures and even environmental samples.
LVL technologies manufactures their 2D datamatrix tubes in the EU using proprietary patented technologies.
Bioreactors and 3D Cell Culture Tools
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m2p-labs │ Microbioreactors
Microbioreactors and automated solutions for screening and bioprocess development.
The mission is to create an intelligent micro fermentation platform.
Flexcell®
Flexcell® specialise in assaying cell tension, compression, and fluid shear systems for cell culturing.
These systems have broad applications in the biomedical research field since strain, compression, or fluid flow have been found to induce biochemical changes in cells derived from a variety of tissues.
IVTech
IVTech’s new LiveBox system is the Next Generation of in-vitro models.
Multi-Organ environment simulation is the great advantage.
The beauty of the LiveBox system is its physiological 3D cell culture environment.
It simulates interaction between human organs in a multi organ environment. Physiological 3D cell culturing makes for a dynamic cell culture.
The LiveBox bioreactors are based on standard 12 or 24 well plate dimensions and offer possibilities for real time monitoring.
3D Bioprinters
REGEMAT 3D is the world leader in the development of bioprinting technologies and its clinical applications. It’s the only company that customizes your printer to your specific application.
Bioprinting has emerged as a promising technology for creating living tissues to regenerate injuries and organs.
Regemat3D printers are designed as modular systems to adapt to your specific requirements.
Contact us for more information
Applications include tissue engineering using spheroids injected onto scaffolds in matrix hydrogels. Spheroids can be used as the “bio-ink” ejected from the nozzle of the bioprinter onto a biocompatible scaffold made out of a hydrogel, layer-by-layer in 3D.
Applications:
- Tissue engineering
- Regenerative Medicine
- Biomaterials Development
- Drug Testing
- Surgical guides, biomodels and prostheses
Original software has been developed by Regemat3D to make scaffold design intuitive and easy to use. Designs are previewed and easy import of geometric shapes is possible.
2D Datamatrix biobank storage tubes
LVL technologies manufactures 2D datamatrix tubes for sample management of high sample throughput (e.g. bio banks ). LVL technologies has developed a unique data matrix tube rack system by making use of the latest technologies and made in the EU by modern injection molding machines, tools and lasers.
Proteomic & Genomic Sample and Enrichment
Application Areas:
Albumin Removal Kits
Hemoglobin Removal Kits
Lipid Removal & Clarification
Urine Protein & Low Abundance Enrichment
Class Specific Enrichment
Sample Prep - Multiple Applications
Functional & Chemical Proteomics
Products are Categorized Within Application Areas
Albumin Removal Kits
Hemoglobin Removal Kits
Lipid Removal & Clarification
Urine Protein & Low Abundance Enrichment
- Urine Protein Enrichment for Proteomics & Biomarkers
- Albumin Depletion Kits from Serum or Plasma
- On-Bead Sample Prep Kit for LC-MS
- Hemoglobin Removal/Depletion Kits
- General Protein Compression
Class Specific Enrichment
- Kinase (& ATP binding proteins) enrichment reagent
- Glycoprotein Enrichment
- Virus and Viral Component Isolation
Sample Prep - Multiple Applications
- Lipid Adsorption & Clarification Reagent
- Protein Removal for Drug Screening & Metabolomics
- SDS and Non-ionic Detergent (eg. Triton) Removal
- Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Proteoglycan Enrichment
Functional & Chemical Proteomicst
- Compound Centric Chemical Proteomics (CCDP) & Protein Compression
- Functional Proteomics Separations and Enrichment Kit
- Polymer Coated silica Affinity Immobilization Matrices
Genomic Sample Prep
- Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Food Safety
- ProCipitate™ -based DNA Isolation Kits
- Virus and Viral Component Isolation
- Lipid adsorption and clarification reagent
Cell Sorting & Separation
pluriStrainer® Cell Strainers
pluriSelect® offers a large variety of cell strainers serving nearly every need.
pluriStrainer® are one of the best cell strainers on the market with many additional features, missed in most comparable basic cell strainers.
pluriStrainer® Mini are the most flexible small cell strainer fitting in nearly any reaction tube (15 ml to 1.5ml, 24 / 48 well plates).
The multi-purpose ÜberStrainer completes the broad spectrum of cell strainer.
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The Mini Strainer have been optimized for small sample volumes. Its unique design allows fitting on a wide variation of tubes, e.g. 1.5 ml /2.0 ml reaction tubes, 15 ml conical centrifuge tubes, 24 well plate and 48 well plate. |
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The pluriStrainer is a sterile sieving device to obtain real single cell suspensions or to remove cell aggregates. It fits into any 50 ml centrifuge (conical) tube and comes with many features. |
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Überstrainer is a sample preparation device that expands the use of mesh tools to increase selection, separation and isolation. Its modular design gives it versatility and a range of functionality. |
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The strainer can be connected to a syringe or a tube via the screw cap with a Luer-Lock adaptor which works under positive or negative pressure. |
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Membrane filters have a well-defined pore size exclusion limit (available with 1, 3, 5 & 8 μm pores), allowing for precise filtration and detection of very small particles. |
pluriBead
pluriBead® offers a robust cell isolation technology for targets from different biological fluids.
Fast target isolation using pluriBead
Our cell separation technology uses non-magnetic pluriBeads.
Our cell separation method consists of four essential steps.
You need a pure cell or protein population for your experiments?
You like to get your targets fast and want a fuss-free isolation system?
- Non-magnetic
- No sample preparation
- No centrifugation
- pluriBeads cannot be taken up by granulocytes
- pluriBeads can be easily and completely detached from the targets
- pluriBeads work in larger sample volumes, e.g. 45ml whole blood or buffy coat
- Purity >95%, viability >95%
- Working at room temperature or 37°C reduces cell stress
Application examples for your lab
- Single Target Cell Isolation
- Simultaneous Isolation of several specific cell types
- RNA Isolation
- DNA Isolation
- Protein Isolation
- Cell Activation
- Cell Depletion
- ELISA
- Immunoprecipitation
Download the pluriSelect 2013 Product Catalogue.
Bead size and surface modification
pluriBead® is using non-magnetic monodisperse microparticles for the sorting of cell mixtures. The surface of the beads is modified with antibodies that recognize specific structures on the cell surface. The beads are larger than the cells and enlarge these artificially. The enlargement by the cells allows a simple separation through sieves and the use of different separation strategies.
During incubation, the cells in suspension are marked with the help of the particles. The targets bonded to the surface of the catcher particles are then separated from all unbound cells through our sieving system. Finally, the target cells are gently detached from the catcher particles with a detachment buffer.
The size of pluriBead® allows easy and rapid separation of cells from whole blood or buffy coat. Pretreatment of blood and blood components, such as the production of a mononuclear cell fraction, is not required, ie, PBMC ( peripheral blood mononuclear cells)made by a density gradient / density centrifugation or other methods of depletion of erythrocytes (e.g. erythrolysis) or target concentration is not required. Moreover, the particle size prevents uptake by endocytosis. The microbeads are available in various sizes and surface modifications.
Ready To Go
Our pluriBead Kit is ready to go.
That means it includes everything that you need for your cell separation (except your sample material).
- Beads
- Washing buffer
- Strainer
- Connecting Ring
- Funnel
Comparison of different sorting Beads
FIVEphoton Biochemicals
FIVEphoton Biochemicals, a domestic and international supplier, provides high quality, reliable and validated research kits and reagents to scientists in life science corporations and academic laboratories to excel in their experimentation.
- Neuroscience
- Pharmacological assays
- Imaging
- Transcript and protein detection
- Reagents to study disease mechanism, particularly age related dimentia disease, mental disorder and brain trauma injury
- Membrane Physiology - Channels
- MEMBRANE POTENTIAL ASSAY KIT - HIGH THROUGHPUT FORMAT
- Fluorescent Dye Membrane Potential Assay Kit
- PATCH CLAMP - ELECTROPHYSIOLOGY
- Expertise and strong commitment to the electrophysiology researcher
- Custom tailored patch pipettes, glass electrodes and capillaries
- Perfusion equipment, bath and intracellular buffers and related technical supplies
- Molecular Reporters
- Novel reactive electrochemical biosensors
- Molecular reporters
- Nucleotide and peptide modifications to investigate protein-protein interaction, transcription factor binding to DNA, ligand-receptor interaction, SNP analysis, DNA hybridization, siRNA detection and PCR analysis. Many of these molecules are unique and are not available elsewhere
- Fluorescent Neurotransmitters
- Research Tools and Services
- ELISA Catalog
- Amyloid, BACE, Synuclein, ApoE, Cyclophilin B, Presenilin, RelA(p65) NF-NF-kB
- Gene Synthesis & Subcloning
- Protein Extraction Reagents
- All protein extraction reagents offered by FIVEphoton Biochemicals extract transmembrane and cytosolic proteins. Due to additional chemical ingredients, the Transmembrane Protein Extraction Reagent (TmPER) will extract and solubilize high molecular weight - multipass transmembrane proteins that are poorly soluble, have aggregation tendency and/or are lipid raft associated. The table below overviews properties of available protein extraction reagents
- NF-kappa B Assays
- Featured Products
- AMYLOID PROTEIN ELISA`KITS
- Dimentia Disease and Amyloid Synthesis and Degradation Pathway ELISA Kits
- Fluorescence, Immunofluorescence
- Biochemicals and Chemicals
- Oligonucleotide Synthesis and Modification Reagents
- General biochemicals, small molecule organics, and chemical libraries
FD Neuro Technologies, Inc.
FD NeuroTechnologies, Inc. is a unique biotechnology company dedicated to the morphological studies of the central nervous system. Established in 1996, their products and services have been utilized internationally. They are highly regarded experts in the fields of neurohistology, neurohistopathology, and immunohistochemistry, with hundreds of citations in peer-review journals. Their most widely cited staining kits include FD Rapid GolgiStain Kit, FD MultiStain Kit, FD NeuroApop Kit, and FD NeuroSilver Kit II.
Exosomes, Virus & Cell Biology
101Bio provide exciting new kits for exosome, virus and cell biology research. They have the best exosome isolation kits on the world market!
The best exosome isolation kits on the world market! This is because you get exciting data using our kits to isolate pure exosome at Higher yield. The yield of exosome is 10 folds more than traditional methods. You can start with 2 mL cell media or 0.2 mL serum and get exosome purity > 95%, even with for plasma, urine, breast milk.
Virus-High® AAV / Adv Release Solution is for fast and efficient harvest of Adenovirus (ADV), Adeno-Associated Virus (AAV), and other non-envelop and non-budding viruses from producing cells. Signalling research - purified protein of human Wnt-3a or 5a, Wingless-type MMTV (mouse mammary tumor virus) or mouse Wnt-3a or 5a.
Transfection Kits
Nucleic acid delivery reagents include ExoFectin® sRNA-into-Exosome Kits - a proprietary formation designed for the delivery of small RNA including miRNA and siRNA into exosomes.
Lentivirus Packaging, 293T Transfection Kit, specifically designed for delivery of lentivirus packaging DNA into 293T cells, to produce high titer lentivirus.
Retrovirus Packaging Kit provides a rapid and convenient method for producing high titers of replication-incompetent retroviruses in only 48 hours.
Lenti Titer-Up to increase Lentivirus titer for ~ 10 folds in virus packaging procedure.
Retro Titer-Up to increase Retrovirus titer for ~ 10 folds in virus packaging procedure.
Neural Stem Cell (hNSC) Human Neural Stem Cells are derived from human induced pluripotent stem cells (hiPSCs) generated by genome footprint-free episomal reprogramming method.
Bioreactor
The CellMaker Range
CellMaker is a revolutionary, single-use, airlift bioreactor technology. This simplifies, accelerates and improves cell culture and fermentation processes. Our system is expertly designed for the life sciences and pharmaceutical industries.
Innovative Airlift Technology
Our patented airlift technology eliminates the need for mechanical mixing, instead using bubbles to gently move cells and nutrients to provide optimal aeration. This enables the rapid growth of cells and optimal production of product expression.
Applications for CellMaker Bioreactors
Microbial Fermentation
Our CellMaker Plus system has been successfully proven with several bacteria (E. Coli, Salmonella, Pseudomonas aeruginosa, Staphylococcus aureus…). The airlift system enables excellent mixing and aeration suitable for both oxygen hungry and anaerobic bacterial processes.
Bacteriophage Amplification
Using the CellMaker, several people have already seen bacteriophage amplified to unprecedented levels in comparison to traditional methods.
Mammalian Cell Culture
Mammalian cell culture requires controlled levels of air, O2 and CO2 gasses coupled with continuous, gentle movement. The CellMaker Plus is perfectly suited for this and have demonstrated excellent results with antibody production from murine hybridoma cell culture for example.
Application notes are available on request.
LVL Technologies - Samplosophy
Samplosophy® 2D Data Matrix tubes from LVL technologies securely stores biospecimens together with systematic sample access. Samplosophy® tubes are designed for long term medical grade care of biological materials, including human biospecimens, animal biospecimens, cell cultures, and even environmental samples. The Samplosophy® biobanking system ensures your sample is reliably maintained to prevent deterioration over time and protected from physical damage, both accidental and intentional.
2D Data Matrix Tubes With Rack & Cover
For over 10 years customers from human, veterinary diagnostics and biopharma areas have been confidence in using uncoded and alphanumeric tubes, as well as tube rack systems, from LVL technologies as a part of their work. Approximately 100 million tubes were used in this period. In response to new demands in Sample Management, in particular for high sample throughput (e.g. bio bank sector), LVL technologies has developed a data matrix tube rack system by making use of the latest technologies, which combine the greatest quality demands with the far unreachable price-performance ratio. In short, a new philosophy in modern Sample Management has risen. Made in the EU by modern injection molding machines, tools and lasers.
LVL 96 Sample Rack with coded tubes 1,2ml
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample Rack with non-coded tubes 1,2ml
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample High Rack with coded tubes 1,2ml
- High rack / flat lid
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample High Rack with non-coded tubes 1,2ml
- High rack / flat lid
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample Rack with coded tubes 0,65ml
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample Rack with non-coded tubes 0,65ml
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample High Rack with coded tubes 0,65ml
- High rack / flat lid
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Sample High Rack with non-coded tubes 0,65ml
- High rack / flat lid
- Material polypropylen (PP)
- SBS-standard suitable for all robotic sample systems
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Frame prevents falling out of tubes
- Lid snaps easily and closes securely
- Stackable, for the use with stacker instruments
- Suitable for side surfaces barcode
- Selectively could be closed with our 8 tube strips, 8x12 cover mats or sealing foil
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Tubes can be ordered as single ones, as 8 tube strips or as a 96 refill system
LVL 96 Refill with coded tubes 1,2ml
- Material polypropylen (PP)
- Tubes are pre-assembled in frame for fast loading of empty racks
- One corner cut away for definite orientation
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Convienent handling and reduced waste
LVL 96 Refill with non-coded tubes 1,2ml
- Material polypropylen (PP)
- Tubes are pre-assembled in frame for fast loading of empty racks
- One corner cut away for definite orientation
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Convienent handling and reduced waste
LVL 96 Refill with coded tubes 0,65ml
- Material polypropylen (PP)
- Tubes are pre-assembled in frame for fast loading of empty racks
- One corner cut away for definite orientation
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Convienent handling and reduced waste
LVL 96 Refill with non-coded tubes 0,65ml
- Material polypropylen (PP)
- Tubes are pre-assembled in frame for fast loading of empty racks
- One corner cut away for definite orientation
- Available with coded or non-coded tubes
- Pressure-tested tightness of tubes
- Autoclavable for 20 min at 121° C, temperature-resistant to -80°C
- Convienent handling and reduced waste
BEOnChip
BEOnChip organ on a chip technology consists of microfluidic cell culture chips that aim to reproduce different physiological responses of organs in-vitro in the lab. They simulate mechanical and chemical conditions to make the environment as biomimetic as possible. Biomimetics is the imitation of systems in nature for the purpose of solving complex human problems.
BE-FLOW
In vitro simulation of physiological environments involving flow and shear stress Long-term 2D experiments in three independent channels under flow conditions.
APPLICATIONS
- Vascular research
- Mechanical shear stress
- Interstitial flow
- Portal - Central vein sinusoids
- Defined liquid Exchange
- Rolling and adhesion
BE- GRADIENT
Interstitial flow is applied through the hydrogel to provide cells with nutrients, O2, and CO2 to maintain optimal conditions.
APPLICATIONS
- Cell migration
- Spheroid substitution
- Necrotic core
- Nutrient, DO2 and drug gradient
- Stem cell differentiation 3D
- Angeogenesis
- Oxidative stress
- Inmune system
TRANSFLOW
A combination of a 2D-3D organized co-culture. It aims to replicate different tissue structures.
Advanced in vitro immune system assays could be possible.
APPLICATIONS
- Cancer-metastasis in vitro model
- SKIN on chip (Animal free testing)
- GUT on chip
- KIDNEY on chip
- BONE on chip
- Wound healing
- Diabetic model
- Brain Blood Barrier
- Toxicity testing
- Absorption in vitro model
- Air-liquid interface
The Next Generation of in-vitro models
IVTech’s new LiveBox system is the Next Generation of in-vitro models.
Multi-Organ environment simulation is the great advantage.
The beauty of the LiveBox system is its physiological 3D cell culture environment.
It simulates interaction between human organs in a multi organ environment. Physiological 3D cell culturing makes for a dynamic cell culture.
The LiveBox bioreactors are based on standard 12 or 24 well plate dimensions and offer possibilities for real time monitoring.
A physiologically 3D dynamic culture has been shown to be more sensitive than in a static cell culture. They are also more resistant to drug candidates than a 2D cell culture.
Down regulation of anti-apoptotic features have been observed in physiologically 3D dynamic cultures.
LiveBox systems have been shown to provide a closer prediction of in-vivo drug efficacy than a 2D static model.
The modularity of the IVTech LiveBox culture systems allows greater accuracy in the study of complex tissue responses such as inflammation and cancer.
Cell Biology
Our ScreenFect® transfection reagents are developed using patented combinatorial chemistry methods, which generates chemical libraries. Using these chemical libraries, candidate reagents are identified by high-throughput cell screening approaches. High performing reagents are further optimized for specific applications.
Our ScreenFect® transfection reagents can be used for transfection of nucleic acid molecules (pDNA, siRNA, mRNA, miRNA) as well as co-transfection of combinations of these.
ScreenFect® reagents provide excellent performance in many standard cell lines as well as difficult-to-transfect primary and stem cells.
Examples of cell lines successfully transfected with ScreenFect® reagents can be found here.
Our ScreenFect® transfection reagents have these performance qualities:
✚ Very high transfection efficiency
✚ Low cytotoxity
✚ Serum compatible and no need to change media
✚ Free of animal derived components
✚ Perfect for high throughput screenings
✚ Perfect for large scale transfection
Cell Stretching Bioreactors
Cell Stretching Bioreactors for Life Science Research
Tension Systems
Flexcell® Tension Systems are patented, computer-regulated bioreactors that apply cyclic or static strain to cells cultured in vitro. We designed Flexcell® Tension Systems to help investigators analyze biochemical changes in response to tensile load on a variety of cell culture applications, including muscle, lung, heart, vascular vessels, skin, tendon, ligament, cartilage, and bone. Our Tension Systems work with UniFlex® (Uniaxial strain) and/or BioFlex® (Equibiaxial strain) culture plates.
Compression Systems
Flexcell’s® Compression System regulates positive air pressure to compress tissue samples or 3D cell cultures in vitro. The FX-5000C™ Compression System compresses samples between a piston and stationary platen using our BioPress™ culture plates. It can load up to 14 lbs. of applied force. Using the FX-5000C™ Compression System, researchers can observe biochemical changes and cell signaling in vitro that mimics in vivo conditions.
Fluid Shear Systems
The Streamer® is a fluid shear stress device allowing users to regulate fluid shear stress to cells in culture with laminar, pulsatile, or oscillating flow. Flexcell’s® Streamer® System uses a computer-controlled peristaltic pump. Together with the Osci-Flow® Flow Controller, researchers can regulate the frequency of oscillation or pulsatile patterns based on shear stress level applied from 0-35 dynes/cm2. Flexcell’s® Fluid Shear System is designed to allow users to observe biochemical changes, cell migration and signaling under fluid shear load in vitro.
PhenoDrive
Novel bio-competent bio-reagents for your cell culture research.
PhenoDrive allows you to control the phenotype of your cells as in their natural micro-environment.
PhenoDrives are a range of fully synthetic, biomimetic materials to provide simple, single step solutions to control your cell culture models and preserve phenotype through mimicry of the extra cellular matrix.
PhenoDrive has been successfully used in both single and co-cultures of a range of cells.
Each PhenoDrive product has been specifically designed to either mimic a separate component of the extra cellular matrix essential for appropriate cell phenotype and function, or to manipulate the cells surrounding milieu to provide an environment that mimics that seen in vivo.
The unique, bespoke design of each PhenoDrive allows the presentation of its bio-cue to the cells to ensure maximum in vivo effect.
Ensuring the preservation of cells
PhenoDrive ensures the preservation of your cells original phenotype, facilitates cell sprouting and their organisation into organoid structures, similar to those seen in vivo.
The products in the PhenoDrive family are specifically tailored to your cell type, in order to understand which PhenoDrive is appropriate for your cells and application we recommend contacting us.
Offering an animal free alternative to cell culture
PhenoDrive products exploit synthetic technology to provide a core product which can be modified to allow the bespoke addition and presentation of active mimics of the extracellular matrix.
Ensuring the preservation of cells
PhenoDrive products ensure the preservation of the cells original phenotype, facilitate cell sprouting and their organisation into structures (organoids) similar to those found in living organisms.
- Bioreactor Systems
- 3D Cell Culture Tools
- 3D Bioprinters
- Cell Sorting & Cell Straining
- Ethical animal free alternative
- Sample Storage - SAFE “Store Aliquots For Ever”
- Neuroscience
- High Content Cell Based Assays
- Crosslinkers
- Exosomes & Cell Biology
- Protein Extraction
- Proteomic & Genomic Sample and Enrichment
- Ethical animal free alternative